All Runewords in Diablo 4: Vessel of Hatred & how to use them

Sam Smith
Diablo 4 runes

Runewords are back, being added to Diablo 4 in the Vessel of Hatred DLC, but how do they work and what does each Rune do?

Those who played Diablo 2 will remember Runewords as being a great way to unlock some unique powers and these have now been added to Diablo 4. Every Rune is an individual item that can be added to the socket of a weapon or a piece of armor. Each one features a different word and by adding multiple Runes to one piece of gear, you can create certain Runewords which each have their own special ability.

While it can be fun to experiment with different Runes many what every Runeword combination brings to the table. So we’ve got all the information you need below.

How do you use Runewords?

To use Runewords you need to mix Rune with two opposing types, Runes of Ritual and Runes of Invocation. Runes of Ritual will have glowing yellow symbols on them while Runes of Invocation feature purple symbols. Yellow Runes will instruct you to complete a certain task while the purple ones will signify the effect mixing those two Runes will have.

For example, a yellow Rune called “Zan” may ask you to cast your Ultimate Skill, while the purple Rune called “Ceh” might feature the power to summon a wolf follower, even though you’re not a Druid class.

Putting them together creates the Runeword ZanCeh and each time you cast your Ultimate Skill, it has the chance to summon the wolf. Mixing different Runewords is a fun and powerful way to make use of various skills your class may not otherwise have access to, and knowing which Runewords to use can complement your build nicely.

Be aware, that you’ll need a resource called “Offering” to trigger your Runeword ability, this is generated by your Rune of Ritual and consumed when your Rune of Invocation uses its power. This means that you’ll need to make sure you have enough Offering for your Runeword to trigger and will need to wait for it to build up again if it depletes.

As some Runes generate more Offering than they use, you can see an overflow where skills can be cast more than once within the same period without needing a cooldown.

Rune of Ritual
Rune of Rituals dictate what action you need to take.

All Runes in Diablo 4

Here’s every Rune of Ritual in Diablo 4 and the trigger for its power:

RuneOfferingTrigger
Ahu10Lucky Hit up to a 100% chance against Injured enemies.
Bac50Move 5 meters
Cem50Cast Evade
Cir25Cast the same non-channeled Skill 3 times in a row
Feo1000Become Injured or Crowd Controlled
Kaa2Lose 1% of your health
Lith25Stand still for less than a second
Moni10Cast a skill after moving
Neo300Deal damage after not taking any within 5 seconds
Noc5Inflict a Crowd Control that isn’t Slow or Chill
Poc2Spend 5% of your Maximum Resource
Tam25Cast a non-Channeled Core Skill
Ur10Your Minion or Companion kills an enemy or dies
Xol150Evoke power from another Class
Yax100Drink a Healing Potion
Yul50Cast a Skill with a Cooldown
Zan150Cast an Ultimate Skill
Rune of Invocation
Rune of Invocation trigger the power when the Runeword is completed.

Here’s every Rune of Ritual you can find in Diablo:

RuneOffering costPower
Ceh100Summon a Spirit Wolf to attack enemies for 8 seconds
Eom100Reduce your active Cooldowns by 0.25 seconds
Gar25Gain 2.5% Critical Strike Chance for 5 seconds, up to 25%
Jah500Replace your next Evade with the Sorcerer’s Teleport, blinking further, dealing damage, and becoming Unstoppable.
Kry500Evoke the Spiritborn’s Vortex, dealing damage and Pulling In enemies
Lac800Evoke the Barbarian’s Challenging Shout, reducing your damage taken
Lum5Restore 1 Primary Resource
Met100Gain a shadow from the Rogue’s Dark Shroud, reducing damage taken per shadow
Mot150Gain a shadow from the Rogue’s Dark Shroud, reducing damage taken per shadow
Ner700Evoke the Rogue’s Countering Concealment, gaining Dodge Chance, Movement Speed, Unstoppable, and Stealth
Ohm500Evoke the Barbarian’s Enhanced War Cry, increasing your Movement Speed and damage dealt
Ono25Evoke the Druid’s Dancing Bolts, seeking and dealing damage to enemies
Qax400Your next non-Basic Skill cast spends all of your Primary Resource to deal up to 100% increased damage
Qua400Evoke the Druid’s Earthen Bulwark, granting yourself a Barrier
Tal100Evoke the Spiritborn’s Pestilent Swarm, dealing damage to enemies
Teb100Evoke the Necromancer’s Abhorrent Iron Maiden, counterattacking damage from enemies and Healing you when they die
Tec100Evoke the Barbarian’s Earthquake, dealing damage to enemies within
Thul400Evoke the Sorcerer’s Mystical Frost Nova, inflicting Freeze and Vulnerable onto enemies
Ton25Evoke the Sorcerer’s Meteorites, dealing damage to enemies
Tun100Evoke the Rogue’s Stun Grenades, Stunning and dealing damage to enemies
Tzic250Evoke the Spiritborn’s Concussive Stomp, dealing damage and Knocking Down enemies
Vex400Gain +3 to all Skills for 5 seconds
Wat100Evoke the Necromancer’s Horrid Decrepify, Slowing enemies, reducing their damage, and letting you Execute them
Xal200Gain 20% Maximum Life for 4 seconds
Xan700Your next Skill cast will be a guaranteed Critical Strike and Overpower
Yom500Evoke the Druid’s Petrify, Stunning enemies and increasing your Critical Strike Damage against them
Zec200Reduce your active Ultimate Cooldown by 4 seconds

Where can I find Runes?

The good news is Runes can be found out in the wilds like any other loot. However, we found that the higher the difficulty, the more drops we received.

We also found a higher frequency of Runes dropped during Helltides, against Elite enemies, and when taking part in other Seasonal or endgame content.

To learn more about the new mechanics in Diablo 4: Vessel of Hatred, check out our guides on the Kurast Undercity, the Dark Citadel, and the new Realmwalker events of Season 6.

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